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Top view image of a man receiving IV drip infusion and vitamin therapy sitting in chair.

<p>NAD+ is having a moment. It is all over longevity podcasts, wellness clinics, and anti-aging discussions, often with claims that range from genuinely interesting to wildly overstated. Here is a grounded look at what it actually is, what the research supports, and why we offer it.</p><h3>What NAD+ Is</h3><p>Nicotinamide Adenine Dinucleotide is a coenzyme present in every living cell. It plays a central role in how your mitochondria produce energy, how your cells repair DNA, and how your body regulates a range of metabolic processes. Without it, basic cellular function breaks down.</p><p>NAD+ levels decline naturally with age. This is well established and not particularly controversial. What is still being actively researched is exactly what that decline contributes to and how much replenishing it matters in practice (Chini et al., 2024).</p><h2><img id="kqt5s93frfmdr5d33s" class="object-cover bg-gray-100" style="font-family: &quot;DM Sans&quot;, sans-serif; font-size: 18px; aspect-ratio: 16 / 9;" src="https://cdn.durable.co/getty/37t8FfpXFsZGmzWxKaxCoplsCVdypNTdiMNNe1Jm0Niw0KD3ziwdksdKv2ddoxdd.jpeg" alt="NAD therapy" data-mce-src="https://cdn.durable.co/getty/37t8FfpXFsZGmzWxKaxCoplsCVdypNTdiMNNe1Jm0Niw0KD3ziwdksdKv2ddoxdd.jpeg" data-mce-style="aspect-ratio: 16/9;"></h2><h3>What the Research Supports</h3><p>The most consistent finding across the literature is that NAD+ supplementation reliably raises NAD+ levels in the body. A placebo-controlled trial found that nicotinamide riboside supplementation increased NAD+ levels in peripheral blood cells by approximately 139%, confirming that delivery does what it is supposed to do at a biochemical level (Martens et al., 2018, cited in Szarvas et al., 2025).</p><p>A 2026 PRISMA-guided systematic review examining 113 eligible studies, including 33 human intervention trials, found that NAD supplementation was generally well tolerated and consistently demonstrated biochemical target engagement, meaning it raises NAD+ levels reliably. Effects on functional outcomes, including energy, metabolism, and cognitive function, were more variable and context dependent (ScienceDirect, 2026).</p><p>Research into NAD+ for neurodegeneration is one of the more promising areas, with ongoing clinical trials examining its role in Alzheimer's and Parkinson's diseases, driven by evidence that deficits in energy metabolism&nbsp;contribute significantly to nervous system degeneration (nad.com, 2025).</p><p>A 2022 study published in Nature Aging found that higher human NAD+ levels were positively associated with healthy aging and muscle function, adding observational support to&nbsp;mechanistic evidence (Janssens et al., 2022).</p><h2><img id="atm59n7xhrmdr5d8ii" class="object-cover bg-gray-100 " style="font-family: &quot;DM Sans&quot;, sans-serif; font-size: 18px; aspect-ratio: 16 / 9;" src="https://cdn.durable.co/getty/2sln1cJU648elX11kiOzfSfXUJdiC3wU2fGIPaO0ekzMsPPQJCgru7VrU9KdHvow.jpeg" alt="brain health" data-mce-src="https://cdn.durable.co/getty/2sln1cJU648elX11kiOzfSfXUJdiC3wU2fGIPaO0ekzMsPPQJCgru7VrU9KdHvow.jpeg" data-mce-style="aspect-ratio: 16/9;"></h2><h3>Where the Evidence Is Still Developing</h3><p>Large-scale randomized controlled trials specifically examining IV NAD+ in healthy adults are limited. A 2020 systematic review noted that most evidence at that point came from small studies rather than rigorous large-scale trials, though the field has moved considerably since then.</p><p>Cognitive function, specifically, is an area where results have been mixed. A 2025 double-blind trial found that NAD+ supplementation did not improve cognitive scores beyond placebo, though medium effect sizes suggested that a larger study might reveal differences (Tavares &amp; Tsotsoros, 2025).&nbsp;</p><p>The practical reality is that NAD+ research is moving quickly, and human trial data are catching up to the substantial preclinical and mechanistic evidence. The biology is compelling. The clinical picture for healthy adults specifically is still being established.</p><figure id="figure-zjrcao241kmdr5dcmh" class=""><img id="zjrcao241kmdr5dcmh" src="https://cdn.durable.co/getty/7HNbYTekRS0j1O9hm2Mrsr5irPS0qBzwi54S803Ohh3ev2DcrNdpRKAADr2sn47A.jpeg" alt="addiction recovery" class="object-cover bg-gray-100 " style="aspect-ratio: 16/9;" data-mce-src="https://cdn.durable.co/getty/7HNbYTekRS0j1O9hm2Mrsr5irPS0qBzwi54S803Ohh3ev2DcrNdpRKAADr2sn47A.jpeg" data-mce-style="aspect-ratio: 16/9;"></figure><h3>What Clients Choose It For</h3><p>At Hyndford Hydration, Driftwood Vitality is our NAD+ infusion, available from 250mg upward. Clients who request it tend to fall into a few groups: those interested in longevity support, those managing significant fatigue or cognitive load, and those incorporating it into a broader wellness protocol.</p><p>It is worth being straightforward about what to expect. NAD+ infusions take time. Allow two to six hours, depending on your dose. Some clients experience flushing or discomfort at higher infusion rates, and your nurse will adjust the infusion rate accordingly throughout the session. It is not a quick top-up infusion. It is a deliberate, time-based session.</p><p>It also requires advanced pharmacy ordering. Contact us at least three weeks before your preferred date.</p><p>IV therapy is supportive in nature. We do not diagnose or treat medical conditions, and we will not claim to do so.</p><p>Serving Nanaimo from Lantzville to Cedar</p><p>All sessions are delivered to your door with no waiting room and no mandatory consultation fees for most clients. Clinical screening is completed before every visit under a valid BC medical directive. Travel is included within our Nanaimo service area. Outside Lantzville to Cedar? Get in touch for a travel quote.</p><p>Interested in Driftwood Vitality? Get in touch before booking, and we will answer your questions honestly.</p><p><strong>Ready? Reserve your infusion today.</strong></p><h3>References</h3><p>Chini, C. C. S., Cordeiro, H. S., Tran, N. L. K., &amp; Chini, E. N. (2024). NAD metabolism: Role in senescence regulation and aging. Aging Cell, 23, e13920.</p><p>Janssens, G. E., Grevendonk, L., Perez, R. Z., Schomakers, B. V., de Vogel-van den Bosch, J., Geurts, J. M. W., et al. (2022). Healthy aging and muscle function are positively associated with NAD+ abundance in humans. Nature Aging, 2(3), 254-263.</p><p>Szarvas, Z., Reyff, Z. A., Peterfi, A., Pinto, C. B., Owens, C. D., Kaposzta, Z., et al. (2025). Effects of NAD+ supplementation with oral nicotinamide riboside on vascular health and cognitive function in older adults with peripheral artery disease. Journal of Pharmacology and Experimental Therapeutics, 392(7), 103607.</p><p>Tavares, K., &amp; Tsotsoros, C. (2025). A double-blind trial to test if NAD+ improves cognition. Innovation in Aging, 9(Suppl 1). https://doi.org/10.1093/geroni/igaf122.3517</p><p>Vinten et al. (2025). Clinical evidence for the use of NAD+ precursors to slow aging. Geromedicine. https://sciexplor.com/articles/Geromedicine.2025.0008</p><p><br data-mce-bogus="1"></p>

Driftwood Vitality: Understanding NAD+ and What the Research Actually Says

Qualified nurse adding a medication to an infusion bottle

<p>Mobile IV therapy is still relatively new to most people in Nanaimo, which means there is a fair amount of misinformation floating around about what it is, who it is for, and whether it is safe. Here are the most common ones we hear.</p><h3>Myth 1: IV Therapy Is Only for People Who Are Seriously Ill</h3><p>This one comes up a lot, probably because most people's experience with IV lines is in a hospital context. Clinical IV therapy and wellness IV therapy share a delivery method but serve different purposes.</p><p>Wellness IV therapy is a supportive service for generally healthy people seeking efficient hydration and nutritional support outside a clinical setting. It is not a medical treatment, and we do not position it as one. The people who book with us are managing demanding schedules, recovering from travel or physical exertion, dealing with chronic conditions that affect hydration, or simply want a more direct and reliable delivery method than oral supplementation. None of that requires being seriously unwell.</p><h3>Myth 2: It Cannot Possibly Be as Safe at Home as in a Clinic</h3><p>The safety of IV therapy comes down to the clinical standards of whoever is administering it, not the building they are standing in.</p><p>At Hyndford Hydration, every session is administered by a BCCNM-regulated nurse with verified clinical IV experience. Vitals are checked on arrival. Sterile technique is used throughout. Your nurse stays with you for the entire session. All treatments are administered under a valid BC medical directive by a licensed Nurse Practitioner, and clinical screening occurs before every visit, without exception.</p><p>The equipment and medications are the same whether you are in a clinic or in your living room. What changes is that you do not have to travel, wait, or sit under fluorescent lighting to receive the same standard of care.</p><h2><img id="k2wli2du2amdr4lllj" class="object-cover bg-gray-100" style="font-family: &quot;DM Sans&quot;, sans-serif; font-size: 18px; aspect-ratio: 16 / 9;" src="https://cdn.durable.co/getty/11Uo6q7Uv12SjkmsPo3hLZwTJlSnuPaoAiRSMgfHPwZnZPEJs8q1bEgZ7ryPseo2.jpeg" alt="mobile iv therapy" data-mce-src="https://cdn.durable.co/getty/11Uo6q7Uv12SjkmsPo3hLZwTJlSnuPaoAiRSMgfHPwZnZPEJs8q1bEgZ7ryPseo2.jpeg" data-mce-style="aspect-ratio: 16/9;"></h2><h3>Myth 3: The Effects Are Just a Placebo</h3><p>This comes up occasionally, and it is worth addressing honestly. Some of what clients report after IV therapy is subjective and difficult to measure in a clinical trial. That is true.</p><p>What is not debatable is the mechanism. IV delivery puts fluid, electrolytes, and nutrients directly into circulation at concentrations that bypass the absorption variables of the digestive system. If you are dehydrated, you get rehydrated efficiently. If your magnesium is depleted, it gets replaced directly. The physiological rationale is sound, and the individual components in our infusions have documented roles in human health. We covered this in detail across our individual ingredient posts if you want to go deeper on the evidence.</p><p>What we will not do is guarantee specific outcomes for any individual. Responses vary, and we will not pretend otherwise.</p><h3>Myth 4: It Is Only for Wealthy People</h3><p>Worth addressing practically. Our infusions start at $175 for plain saline and $90 for IM injections.&nbsp; We understand it is a considered purchase for most people.</p><p>What it is not is a frivolous expense. A clinical service administered by a regulated nurse, delivered to your door, with medical oversight on every treatment and no mandatory consultation fees for most clients. The pricing reflects what it actually costs to do properly, not what it costs to cut corners.</p><p>We also offer group discounts, bundle pricing for repeat clients, and IM add-ons at significantly reduced rates when added to an IV visit. If cost is a concern, get in touch, and we will find an option that makes sense.</p><h3>Myth 5: Anyone Can Do This; It Is Not Really Nursing</h3><p>Starting an IV line, monitoring a client throughout an infusion, assessing for adverse reactions, and making real-time clinical decisions requires actual nursing training and experience. It is not a skill you pick up at a weekend certification course.</p><p>Every Hyndford Hydration nurse is BCCNM-regulated with verified clinical IV experience. Medical oversight is provided by a BC-licensed Nurse Practitioner on every treatment. It is a clinical service delivered in a non-clinical setting, and the standard of care reflects that.</p><p>IV and IM therapy is supportive in nature. We do not diagnose or treat medical conditions, and we will not claim to do so.</p><p>All sessions are delivered to your door with no waiting room and no mandatory consultation fees for most clients. Clinical screening is completed before every visit under a valid BC medical directive. Travel is included within our Nanaimo service area. Outside Lantzville to Cedar? Get in touch for a travel quote.</p><p>Have a look at our <a data-mce-href="https://hyndfordhydration.ca/infusion-menu" href="https://hyndfordhydration.ca/infusion-menu" target="_blank" rel="noopener">Signature Infusions</a> or get in touch with questions.</p><h3><strong>Ready?<a data-mce-href="https://clientportal.us.zandahealth.com/clientportal/hyndfordhydration" href="https://clientportal.us.zandahealth.com/clientportal/hyndfordhydration" target="_blank" rel="noopener"> Reserve your infusion today.﻿</a></strong></h3><p><br></p>

Mobile IV Therapy in Nanaimo: Some Myths Worth Addressing

Hyndford Hydration Home IV Therapy

Hyndford Hydration is a nurse-led mobile IV and IM therapy service based in Nanaimo, BC. We deliver clinically grounded infusions and injections to your home, hotel, workplace, or event, administered by BCCNM-regulated nurses under a valid BC medical directive. Our menu includes hydration infusions, Myers Cocktail, Vitamin C, Glutathione, Magnesium, NAD+, Alpha-Lipoic Acid, and a full range of IM injections including B12, Vitamin D3, B-Complex, and Glutathione. Group and event packages available for corporate wellness, weddings, and athletic recovery. Serving Nanaimo from Lantzville to Cedar.

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Driftwood Vitality: Understanding NAD+ and What the Resea...

Mobile IV Therapy in Nanaimo: Some Myths Worth Addressing